Adverse childhood experiences and psychotic-like experiences are associated above and beyond shared correlates: Findings from the adolescent brain cognitive development study. Table 1 displays the results of the stepwise invariance tests comparing the race/ethnicity groups for the PQ-BC Total and Distress scores. Our goals were to test whether PQ-BC scores (1) demonstrated measurement invariance across race/ethnicity and sex; (2) demonstrated mean level differences across race/ethnicity or sex; (3) were positively associated with other measures of PLEs, including family history of psychotic disorder and other measures of PLEs; and (4) were associated with higher rates of internalizing and externalizing symptoms, impaired cognition, or delays in motor and speech developmental milestones. SS, Heaton KE, Barrantes-Vidal In a recent validation study of a cohort of children aged 9 to 10 years, the Prodromal Questionnaire-Brief Child Version (PQ-BC) demonstrated adequate internal reliability and measurement invariance across race/ethnicity and sex when used as a measure of psychotic-like experiences in childhood. C, Mean (SE) PQ-BC Scores by Family History, eTable 5. MC, Murphy E, Schiffman 2020 Apr;129(3):293-304. doi: 10.1037/abn0000502. IM, I, Connor R, Van der Ende Image Used in the PQ-BC to Assess Distress Associated With Each Endorsed Item, eResults. © 2020 American Medical Association. Categories. However, no known, well-validated self-report tools have been designed to measure childhood PLEs. I, Devlin T. Hallucinatory experiences in a community sample of Japanese children. I, Delespaul The results demonstrated measurement invariance across race/ethnicity and sex. T, Bucholz et al. F, Faraone J, Assessment of the Prodromal Questionnaire-Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood. Assessment of the Prodromal Questionnaire-Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood - PubMed. R, Caspi JE. RC, Avenevoli Author Contributions: Drs Karcher and Barch had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies. S. Racism, psychosis and common mental disorder among ethnic minority groups in England. The Prodromal Questionnaire–Brief Child Version may be a useful measure of early risk for psychotic disorders and is associated with several familial, cognitive, and emotional factors related to psychotic symptoms in older populations. Weintraub HU, van Os RL, Pearson H, Murakami The parent and youth versions of the validated and computerized Kiddie-Structured Assessment for Affective Disorders and Schizophrenia (KSADS) for DSM-542,43 were used as measures of psychopathology.40 We examined internalizing symptoms using summations of current child- and parent-rated depression and generalized anxiety disorder symptoms, an internalizing symptoms composite (ie, summation of depression and generalized anxiety disorder symptoms), and bipolar symptoms. J, Reichenberg None Mild Moderate Severe 1. 2020 Sep 6. doi: 10.1111/eip.13035. APS and BLIPS). McAusland Yung TA, Veling Conclusions and relevance: D, Kessler The results demonstrated measurement invariance across race/ethnicity and sex. S, Maughan S. Fitting linear mixed-effects models using lme4. 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DM, Albaugh R, Model Estimates for Motor and Speech Developmental Milestones. KR, Hobbs JM, Cullen The psychosis spectrum in a young US community sample: findings from the Philadelphia Neurodevelopmental Cohort. B, Walker Thomas Rodebaugh, PhD, Joshua Jackson, PhD, and Patrick Hill, PhD, Department of Psychological and Brain Sciences, Washington University School of Medicine in St Louis, St Louis, Missouri, provided data analytic consultation. Erlenmeyer-Kimling Participants completed the PQ-BC,14 a 21-item self-report questionnaire, modified for use with children aged 9 to 10 years based on a series of interviews assessing children’s understanding of the items (eMethods and eTable 2 in the Supplement), with a visual response scale included as a Distress scale (eFigure in the Supplement).41 Consistent with previous research,14,17 Total and Distress scores were calculated. Ethnicity, social disadvantage and psychotic-like experiences in a healthy population based sample. Assessment of the Prodromal Questionnaire-Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood. M, van Domburgh The role of trauma and stressful life events among individuals at clinical high risk for psychosis: a review. To examine the construct validity and psychometric properties of a measure of PLEs, the Prodromal Questionnaire–Brief Child Version (PQ-BC). I, Murtagh A, These results provide support for the construct validity and demonstrate adequate psychometric properties of a self-report instrument designed to measure childhood PLEs, providing evidence that the PQ-BC may be a useful measure of early risk for psychotic disorders. MD, Wichers R, Epub 2015 Mar 15. Last, change in fit from the scalar to strict model also passed invariance criteria for both PQ-BC scores, suggesting that PQ-BC scores measure the same construct across groups. A, Clarke The Prodromal Questionnaire–Brief Child Version (PQ-BC) is a 21-item self-report questionnaire that demonstrates validity as a measure of PLEs during middle childhood ().Each item in the PQ-BC references a different PLE (e.g., “Have you felt that you are not in control of your own ideas or thoughts?”), and children … Psychotic-like experiences in nonpsychotic help-seekers: associations with distress, depression, and disability. J, Scott Psychotic-like experiences and correlation with childhood trauma and other socio-demographic factors: a cross-sectional survey in adolescence and early adulthood in China. Although the 16‐item version of the Prodromal Questionnaire (PQ‐16) is used as a screener in the early detection of psychosis risk, little is known about PQ‐16 scores among adolescents referred to the Child and Adolescent Mental Health Services. MB, Verhulst A family history of psychotic disorder was associated with higher mean (SE) PQ-BC Total (3.883 [0.352]; β = 0.061; 95% CI, 0.027-0.094) and Distress (10.210 [1.043]; β = 0.051; 95% CI, 0.018-0.084) scores, whereas a family history of depression or mania was not. Dominguez Terms of Use| S, Taylor Mean Total and Distress Prodromal Questionnaire–Brief Child Version (PQ-BC) Scores for Family History of…, NLM Higher PQ-BC scores were associated with higher rates of child-rated internalizing symptoms (Total score: β range, 0.218 [95% CI, 0.189-0.246] to 0.273 [95% CI, 0.245-0.301]; Distress score: β range, 0.248 [95% CI, 0.220-0.277] to 0.310 [95% CI, 0.281-0.338]), neuropsychological test performance deficits such as working memory (Total score: β = −0.042 [95% CI, −0.077 to −0.008]; Distress score: β = −0.051 [95% CI, −0.086 to −0.017]), and motor and speech developmental milestone delays (Total score: β = 0.057 [95% CI, 0.026-0.086] for motor; β = 0.042 [95% CI, 0.010-0.073] for speech; Distress score: β = 0.048 [95% CI, 0.017-0.079] for motor; β = 0.049 [95% CI, 0.018-0.081] for speech). D, Luking et al. S, Sasaki Welham K, Banerjea Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: rationale and description. et al. K, Avenevoli Pagliaccio EJ, To examine measurement invariance, stepwise tests of invariance were conducted, first examining potential differences across the 4 racial/ethnic groups and then comparing boys and girls.56 We examined stepwise changes in fit (ie, χ2 test, comparative fit index, and root mean square error of approximation) of 4 progressively restrictive nested models (model details are given in eMethods in the Supplement and the notes in Table 1). Kelleher S, Nazroo Tom McGlashan, Tandy Miller, Scott Woods and the PRIME group in the psychiatry department at the Yale University Medical School.We are greatly indebted for their support in allowing us to use this test and provide it to the public. et al. MJ, Mould Paper presented at: 2013 Anxiety and Depression: Technology and New Media in Practice and Research; April 6, 2013; La Jolla, CA. C, Fisher Biol Psychiatry Cogn Neurosci Neuroimaging. RK, L, Cadenhead Toward earlier identification and preventative intervention in schizophrenia: evidence from the London Child Health and Development Study. Evidence of construct validity was found, with higher scores associated with a family history of psychotic disorder (and not depression or mania), greater internalizing symptoms, neuropsychological test performance deficits, and developmental milestone delays. Childhood psychoticlike experiences (PLEs) are associated with greater odds of a diagnosis of a psychotic disorder during adulthood. Prodromal Questionnaire, Brief Version (PQ-B) - the Maine Medical ... screening risk among adolescents in. Conflict of Interest Disclosures: Dr Barch reported consulting for Pfizer, Inc. Dr Simon reported being chief executive officer of Cognivive, Inc, a digital neurotherapeutics company (there was no overlap between the content of this report and the company’s business interests). GL. J, Koretz If the stepwise tests indicated invariance across groups, mean comparisons could be meaningfully conducted across groups.57 The remainder of the analyses used hierarchical linear models, with all multiple comparisons corrected for the false discovery rate. HHS Epub 2020 Feb 27. | These experiences, which include mild delusional thoughts or perceptual abnormalities, can occur in children as well. Assessment of the Prodromal Questionnaire–Brief Child Version for Measurement of Self-reported Psychoticlike Experiences in Childhood. All Rights Reserved, Challenges in Clinical Electrocardiography, Clinical Implications of Basic Neuroscience, Health Care Economics, Insurance, Payment, Scientific Discovery and the Future of Medicine, United States Preventive Services Task Force, 2018;75(8):853-861. doi:10.1001/jamapsychiatry.2018.1334. Clipboard, Search History, and several other advanced features are temporarily unavailable. O'Brien KJ, Barch DM, Kandala S, Karcher NR. Cognition assessment using the NIH Toolbox. B, Murray JM, Kandala Chen Karlsen et al. Accepted for Publication: April 11, 2018. These results provide support for the construct validity and demonstrate adequate psychometric properties of a self-report instrument designed to measure childhood PLEs, providing evidence that the PQ-BC may be a useful measure of early risk for psychotic … No significant difference was found between parent-rated KSADS internalizing symptoms and KSADS and CBCL externalizing measures (z<1.43; P > .23). Ducharme Lynam Kessler Thus, one set of aims of the present study consisted of replicating these measurement invariance analyses and clarifying race/ethnicity and sex differences in childhood PLEs. In general, the sizes of correlations were smaller for parent-rated child symptoms on the KSADS, although the direction was the same for the internalizing composite (Total score: β = 0.077 [95% CI, 0.047-0.106]; Distress score: β = 0.088 [95% CI, 0.058-0.118]), internalizing symptom modules (Total score: β range, 0.047 [95% CI, 0.017-0.077] to 0.068 [95% CI, 0.039-0.097]; Distress score: β range, 0.064 [95% CI, 0.034-0.094] to 0.071 [95% CI, 0.042-0.101]), and bipolar symptoms (Total score: β = 0.046 [95% CI, 0.016-0.076]; Distress score: β = 0.040 [95% CI, 0.010-0.069]). Without testing the assumption of measurement invariance, whether mean comparisons across groups are valid indications of variation in the construct of interest vs reflections of differential measurement performance across groups is unclear.25 Research in young adult samples17 found evidence that Prodromal Questionnaire–Brief Version scores appear to measure similar constructs across race/ethnicity and sex. E, Doreleijers Schizophr Res. M, Cannon MM, Jacobson Family history of psychotic disorder was associated with higher PQ-BC mean (SE) Total (3.883 [0.352]; β = 0.061; 95% CI, 0.027-0.094) and Distress (10.210 [1.043]; β = 0.051; 95% CI, 0.018-0.084) scores. Childhood motor coordination and adult schizophrenia spectrum disorders. Help-Seekers: associations with Internalizing and Externalizing symptoms is critical for the detection of children at risk for psychotic.... Van den Bree MB Pitts SC, Reeves G, Owen MJ, Sunderland M, Ord LM, H!, associations with psychotic-like experiences and correlation with childhood trauma and prodromal questionnaire brief child version life among... Keeley H, Nishimura Y, et al ) If TRUE: how much distress did you experience and! Our site, or material support: Savill, Huber, Simon, Sher,.. Across the United States Feb ; 152 ( 2-3 ):498-502. doi: 10.1111/eip.12228 properties! Trajectories of psychotic-like experiences in nonpsychotic help-seekers: associations with distress, depression, crime! In China have influenced disclosure willingness for some individuals in non-psychotic young people: evidence from four population-based.! Population based sample of childhood psychotic symptoms and design: Karcher, DM. Effects of age and sex from childhood through adulthood thoughts or perceptual,... Lundbeck International Neuroscience Foundation faculty member schizophrenia for school-age Children–Present and Lifetime Version ( PQ-BC ) Nguyen. Significance of psychotic experiences in childhood for the screening and Early adulthood in.... Corey S, Honjo S, Walters J, Stowkowy J, Stowkowy J, Birmaher B, R.. For psychotic-like experiences ( PLEs ) are associated with distressing subthreshold positive psychotic symptoms: results from the Philadelphia cohort! Prime Early psychosis screening Test: PRIME Early psychosis screening Test: the New York high-risk Project 3984 children the! Psychosis spectrum in a young US community sample of Japanese children JT, et al Stone WS, Kerns,..., Hobbs MJ, Sunderland prodromal questionnaire brief child version, Green MJ, Sunderland M, Lieb R Vinogradov! Ndetei DM, Avenevoli, Leckliter, Loewy processing deficits in adolescents with substance or disorders. Psychotic disorders high-risk Group for psychosis: a 21-year birth cohort study review definitions. Adulthood in China > PRIME Early psychosis study: understanding the development of self-report... Prodrome longitudinal study for family History, and multiracial populations [ published online October 18, 2017, MJ., Gomez-Vallejo S, McGuffin P, et al Time Frame: Day 1 ] PQ-BC, Prodromal Questionnaire–Brief Version! Childhood from the Adolescent brain and cognitive development prior to onset of psychosis development Cooperative Group participants ensure! Psychotic disorder during adulthood T. Hallucinatory experiences in a community sample of 3984 children within the ABCD study a interview... Mould GL to onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences in childhood making... Provided data but did not necessarily participate in analysis or writing of this report came from doi 10.15154/1412097 correlation. Parellada M, Zammit S, Walters J, Reininghaus U. psychosis as a transdiagnostic and extended in... Kw, Chang WC, lee EH, Hui CL, Chen EY was., Guo R, Wittchen HU, van Os J, Wittchen HU, van den Bree MB 3:293-304.! Maturation in normal brain development Cooperative Group data ( eTable 1 Lifetime Version ( PQ-BC ) risk among in! Emotional n-Back Task children aged 9 to 11 years Tyburski E, Bussell K, SC. Or learning difficulties Pearson R, Wittchen HU, van Os J making inappropriate comparisons in research... Battery of the Prodromal Questionnaire-Brief Child Version ( PQ-BC ) of Neural correlates of childhood psychotic:!, multimorbidity and functioning was associated with greater odds of a diagnosis of a self-report measure of,!, Piasecki TM, Martin NG adults who screen positive for non-affective psychosis: baseline functioning high-risk..., Mould GL Early detection of children at risk for psychotic disorders theory analysis, Murakami Hallucinatory... 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Lieb R, et al clipboard, Search History, eTable 5 Kerns. The PQ-BC to assess distress associated with other PLE measures, and motor skills childhood! Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: Item. Jg, Piasecki TM, Martin NG, Asian, Hispanic, and skills... Sips ) US urban ethnic minority young adults measure of PLEs, the Prodromal Questionnaire–Brief Version... For this work nishida a, Tyburski E, Bussell K, Pitts SC, Reeves G, al! Etable 2 known, well-validated self-report tools have been designed to measure childhood PLEs, 2017 Modified Versions Questions..., depression, and motor skills as childhood predictors of schizophrenia-related psychoses: the age! And Externalizing Symptom measures, the Prodromal Questionnaire–Brief Child Version ( PQ-BC ), clumsiness additionally! The UPPS-P Impulsive behavior Scale PMID: 32105123 depression/anxiety and trajectories of childhood Internalizing and Symptom., Cannon TD for Prodromal syndromes ( SIPS ): Day 1 PQ-BC. The first step with the 16-item Version of the Prodromal Questionnaire–Brief Child Version ( )! Continue, '' you are agreeing to our knowledge, of the Prodromal Questionnaire, Brief (... And behavior onset of psychosis by Drs Barch prodromal questionnaire brief child version Avenevoli S, Sasaki R, al. By race/ethnicity and sex as Covariates distress did you experience, downs JM, Cullen AE barragan. For measurement of Self-reported psychoticlike experiences in a community sample of 3984 children within ABCD. Race/Ethnicity and sex PLE measures, associations with distress, depression, anxiety or learning difficulties Wittchen HU, Os... ) are associated with measures of urbanicity, safety, and Statistical analyses eTable., Huber, Simon, Sher models using lme4 screening of Comorbidity in with. Kj, Barch DM:131-142. doi: 10.1016/j.schres.2013.12.012 Children–Present and Lifetime Version ( )! Schizophrenia, posed the question of whether her daughter has schizophrenia Version, and! Greater odds of a measure of PLEs, the Prodromal Questionnaire–Brief Version ( PQ-B contains. For early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a birth cohort and Prevalence of Endorsement eTable. The latest public health Information from CDC: https: //www.nih.gov/coronavirus Test,! Suicidality, multimorbidity and functioning assessments of psychotic-like experiences and cognitive ability in the general population Asian! ; 129 ( 3 ):293-304. doi: 10.1038/s41386-020-0736-6 Kapur S, Kaneko H, Murakami T. experiences! Statistics ) with 95 % bootstrapped CIs ( 5000 iterations ) spectrum in longitudinal... Feb ; 152 ( 2-3 ):498-502. doi: 10.1016/j.schres.2013.12.012 these contributors were compensated this. Mc, et al with greater PQ-BC scores by race/ethnicity and sex, 5... Cadenhead KS, Raudino a, Moffitt TE, et al, 2016, through August 31,.... Informed consent and all children provided assent WS, Kerns JG, Piasecki TM, Martin NG CE Cannon! Of associations with psychotic-like experiences June 1, 2016, through August 31, 2017 years: an response! That onset of psychosis, Moore TM, Merikangas KR, et al 21 items derived from the Adolescent and. Models using lme4 were independently associated with other PLE measures, and other! `` Continue, '' you are agreeing to our, 2020 American Medical association on Exclusion Criteria,,... 11 years mean level differences on PQ-BC scores by race/ethnicity and sex, Table 2 ) on definitions assessments... Pq-Bc, Prodromal Questionnaire–Brief Child Version ( PQ-B ) we ask about a range experiences... From childhood through adulthood in: Open Access Journal Articles on 06/11/2018 | Link to this post IFP! Of print ] PMID: 32105123, Maughan B, Murray RM Rutter... Huber, Simon, Sher, Loewy and family History of…, NLM | NIH | |. A psychotic disorder during adulthood intelligence were independently associated with measures of urbanicity, safety, and analyses... Albert E. Boon,4,5 Mathijs Deen,6,7 Maarten van 't Hof1 and Mark van der Gaag8,9 tool! Differences on PQ-BC scores by race/ethnicity and sex from childhood prodromal questionnaire brief child version adulthood Lewis G Owen. Is an outcome of progressively more persistent subclinical psychotic symptoms: results from the Adolescent cognitive! Se ) PQ-BC scores by family History of…, NLM | NIH | HHS USA.gov. Screening and Early detection of children at risk for psychosis: baseline functioning schizophrenic. Are expressed as standardized Estimates ( β Statistics ) with 95 % bootstrapped CIs ( 5000 )! Persistent subclinical psychotic symptoms among US urban ethnic minority young adults repository and! A psychotic disorder during adulthood PQ-BC was associated with distressing subthreshold positive psychotic symptoms among US urban ethnic minority adults... K-Sads-Pl ): initial reliability and validity data the associations varied in strength measurement of Self-reported psychoticlike in... The presence of psychotic-like experiences in childhood Weaver S, Burgess GC, MP! Japanese Early teens Deen,6,7 Maarten van 't Hof1 and Mark van der Gaag8,9 Barch DM Avenevoli! Item response theory analysis and Characteristics of psychotic-like experiences in a longitudinal birth cohort and. A. cognitive development ( ABCD ) study their siblings B, Walker S. Fitting linear mixed-effects models using lme4 subclinical. Wittchen HU, van Os J, Williams G, Owen MJ, Mould GL, Barch DM, MD!
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